Kodi phenoxyethanol ndi yowopsa pakhungu?

Ndi chiyaniphenoxyethanol?
Phenoxyethanol ndi glycol ether yopangidwa mwa kuphatikiza magulu a phenolic ndi ethanol, ndipo imawoneka ngati mafuta kapena mucilage mumadzi ake.Ndi zodzitetezera wamba mu zodzoladzola, ndipo angapezeke mu chirichonse kuchokera nkhope creams kuti lotions.
Phenoxyethanol imakwaniritsa kusungirako kwake osati kudzera mu antioxidant koma kudzera mu ntchito yake yolimbana ndi tizilombo toyambitsa matenda, yomwe imalepheretsa komanso imachotsanso ma microorganisms akuluakulu a gram-positive ndi negative.Zimakhalanso ndi mphamvu yolepheretsa kwambiri mabakiteriya osiyanasiyana monga E. coli ndi Staphylococcus aureus.
Kodi phenoxyethanol ndi yowopsa pakhungu?
Phenoxyethanol imatha kupha munthu akamamwa kwambiri.Komabe, topical ntchitophenoxyethanolpa ndende zosakwana 1.0% akadali mkati mwaotetezeka.
Takambirana kale ngati ethanol imapangidwa ndi acetaldehyde wambiri pakhungu komanso ngati imatengedwa mochuluka ndi khungu.Zonsezi ndizofunikira kwambiri pa phenoxyethanol.Pakhungu lomwe lili ndi chotchinga chokhazikika, phenoxyethanol ndi imodzi mwama glycol ethers omwe amawononga kwambiri.Ngati njira ya metabolism ya phenoxyethanol ikufanana ndi ya ethanol, sitepe yotsatira ndiyo kupanga acetaldehyde yosakhazikika, yotsatiridwa ndi phenoxyacetic acid ndi zina zopanda malire.
Osadandaula panobe!Titakambirana kale retinol, tidatchulanso dongosolo la enzyme lomwe limakhudzana ndi metabolism yaphenoxyethanol, ndi kuti njira zosinthira izi zimachitika pansi pa stratum corneum.Chifukwa chake tiyenera kudziwa kuchuluka kwa phenoxyethanol komwe kumatengera transdermally.Pakafukufuku wina yemwe adayesa kuyamwa kwa chosindikizira chochokera m'madzi chokhala ndi phenoxyethanol ndi zinthu zina zotsutsana ndi tizilombo toyambitsa matenda, khungu la nkhumba (lomwe lili ndi mphamvu yapafupi kwambiri ya anthu) limatha kuyamwa 2% phenoxyethanol, yomwe idakweranso mpaka 1.4% pambuyo pa maola 6, ndi 11.3% pambuyo pa maola 28.
Maphunzirowa akuwonetsa kuti kuyamwa ndi kutembenuka kwaphenoxyethanolpa ndende zosakwana 1% si mkulu mokwanira kupanga zoipa Mlingo wa metabolites.Zotsatira zofananazi zapezedwanso m'maphunziro ogwiritsa ntchito makanda obadwa kumene osakwana milungu 27.Phunzirolo linati, "Aqueousphenoxyethanolsichimayambitsa kuwonongeka kwakukulu kwa khungu poyerekeza ndi zotetezera zomwe zili ndi ethanol.Phenoxyethanol imalowetsedwa pakhungu la makanda obadwa kumene, koma sapanga makutidwe ndi okosijeni a phenoxyacetic acid kwambiri." Zotsatirazi zikuwonetsanso kuti phenoxyethanol imakhala ndi chiwopsezo chachikulu kwambiri cha metabolism pakhungu ndipo sichiwononga kwambiri. gwirani, mukuwopa chiyani?
Ndani ali bwino, phenoxyethanol kapena mowa?
Ngakhale phenoxyethanol imapangidwa mwachangu kuposa ethanol, kuchuluka koletsedwa kwapamutu kumatsika kwambiri ndi 1%, kotero sikufananiza bwino.Popeza stratum corneum imalepheretsa mamolekyu ambiri kuti asatengeke, ma free radicals opangidwa ndi awiriwa ndi ochepa kwambiri kuposa omwe amapangidwa ndi zochita zawo za okosijeni tsiku lililonse!Komanso, chifukwa phenoxyethanol ili ndi magulu a phenolic mu mawonekedwe a mafuta, imasanduka nthunzi ndikuuma pang'onopang'ono.
Chidule
Phenoxyethanol ndi mankhwala omwe amagwiritsidwa ntchito mu zodzoladzola.Ndi yotetezeka komanso yothandiza, ndipo ndi yachiwiri kwa parabens pakugwiritsa ntchito.Ngakhale ndikuganiza kuti ma parabens ndi otetezeka, ngati mukuyang'ana zinthu zopanda parabens, phenoxyethanol ndi chisankho chabwino!