Kodi phenoxyethanol ndi yovulaza khungu?

Kodi ndi chiyaniphenoxyethanol?
Phenoxyethanol ndi glycol ether yomwe imapangidwa pophatikiza magulu a phenolic ndi ethanol, ndipo imawoneka ngati mafuta kapena mucilage mu mkhalidwe wake wamadzimadzi. Ndi chosungira chodziwika bwino mu zodzoladzola, ndipo chimapezeka mu chilichonse kuyambira mafuta odzola kumaso mpaka mafuta odzola.
Phenoxyethanol imakwaniritsa mphamvu yake yosungira osati kudzera mu antioxidant koma kudzera mu mphamvu yake yolimbana ndi tizilombo toyambitsa matenda, zomwe zimaletsa komanso kuchotsa ma microorganism ambiri a gramu-positive ndi negative. Imakhalanso ndi mphamvu yoletsa mabakiteriya osiyanasiyana ofala monga E. coli ndi Staphylococcus aureus.
Kodi phenoxyethanol ndi yovulaza khungu?
Phenoxyethanol ikhoza kupha munthu akaimeza pa mlingo waukulu. Komabe, kugwiritsa ntchito pamwamba pa madziphenoxyethanolpa kuchuluka kwa mankhwala osakwana 1.0% akadali mkati mwa mulingo wotetezeka.
Takambirana kale ngati ethanol imasinthidwa kukhala acetaldehyde pakhungu kwambiri komanso ngati imayamwa kwambiri ndi khungu. Zonsezi ndizofunikira kwambiri pa phenoxyethanol. Pakhungu lomwe lili ndi chotchinga chosatha, phenoxyethanol ndi imodzi mwa ma glycol ethers omwe amawononga mwachangu kwambiri. Ngati njira ya kagayidwe ka phenoxyethanol ndi yofanana ndi ya ethanol, gawo lotsatira ndi kupanga acetaldehyde yosakhazikika, kutsatiridwa ndi phenoxyacetic acid ndi ma free radicals ena.
Musadandaule pano! Pamene tidakambirana za retinol kale, tidatchulanso za dongosolo la ma enzyme lomwe limagwirizanitsidwa ndi kagayidwe kachakudya kaphenoxyethanol, ndi kuti njira zosinthira izi zimachitika pansi pa stratum corneum. Chifukwa chake tifunika kudziwa kuchuluka kwa phenoxyethanol komwe kumayamwa kudzera mu transdermal. Mu kafukufuku wina yemwe adayesa kuyamwa kwa sealant yochokera m'madzi yokhala ndi phenoxyethanol ndi zosakaniza zina zotsutsana ndi tizilombo toyambitsa matenda, khungu la nkhumba (lomwe lili ndi mphamvu yolowera kwambiri kuposa anthu) lingatenge 2% ya phenoxyethanol, yomwe idakweranso kufika pa 1.4% yokha patatha maola 6, ndi 11.3% patatha maola 28.
Maphunziro awa akusonyeza kuti kuyamwa ndi kusintha kwaphenoxyethanolPa kuchuluka kwa mankhwala osakwana 1% sikokwanira kupanga mankhwala owopsa a metabolites. Zotsatira zofananazi zapezekanso m'maphunziro ogwiritsa ntchito makanda obadwa kumene osakwana milungu 27. Kafukufukuyu adati, "Amadzimadziphenoxyethanolsichimayambitsa kuwonongeka kwakukulu pakhungu poyerekeza ndi zosungira zochokera ku ethanol. Phenoxyethanol imalowa m'khungu la makanda obadwa kumene, koma siimapanga phenoxyacetic acid yopangidwa ndi okosijeni kwambiri." Zotsatirazi zikuwonetsanso kuti phenoxyethanol ili ndi kuchuluka kwakukulu kwa kagayidwe kachakudya pakhungu ndipo siimayambitsa kuwonongeka kwakukulu. Ngati makanda angathe kuthana nazo, mukuopa chiyani?
Ndani wabwino kuposa iye, phenoxyethanol kapena mowa?
Ngakhale phenoxyethanol imasinthidwa mwachangu kuposa ethanol, kuchuluka kwakukulu kocheperako komwe kumagwiritsidwa ntchito pakhungu ndi kochepa kwambiri pa 1%, kotero si kufananiza kwabwino. Popeza stratum corneum imaletsa mamolekyu ambiri kuti asayamwe, ma free radicals omwe amapangidwa ndi awiriwa ndi ochepa kwambiri kuposa omwe amapangidwa ndi ma oxidation reaction awo tsiku lililonse! Komanso, chifukwa phenoxyethanol ili ndi magulu a phenolic mu mawonekedwe a mafuta, imaphwanyika ndikuuma pang'onopang'ono.
Chidule
Phenoxyethanol ndi mankhwala oteteza omwe amagwiritsidwa ntchito kwambiri mu zodzoladzola. Ndi otetezeka komanso ogwira ntchito, ndipo ndi achiwiri kwa parabens pankhani yogwiritsira ntchito. Ngakhale ndikuganiza kuti parabens ndi otetezeka, ngati mukufuna zinthu zopanda parabens, phenoxyethanol ndi chisankho chabwino!