Formaldehyde ndi glutaraldehydeonse ndi mankhwala omwe amagwiritsidwa ntchito ngati njira zolumikizirana pazinthu zosiyanasiyana, makamaka pankhani ya biology, chemistry, ndi sayansi yazinthu.Ngakhale amagwira ntchito zofananira pakuphatikiza ma biomolecules ndikusunga zitsanzo zachilengedwe, ali ndi mawonekedwe apadera amankhwala, kuyambiransoko, kawopsedwe, ndi ntchito.
Zofanana:
Crosslinking Agents: Onse formaldehyde ndiglutaraldehyde ndi aldehydes, kutanthauza kuti ali ndi gulu la carbonyl (-CHO) kumapeto kwa mapangidwe awo a maselo.Ntchito yawo yayikulu ndikupanga maubwenzi ogwirizana pakati pamagulu ogwira ntchito a ma biomolecules, zomwe zimapangitsa kulumikizana.Crosslinking ndiyofunikira pakukhazikika kwa zitsanzo zachilengedwe, kuzipangitsa kukhala zolimba komanso zolimba pakuwonongeka.
Kugwiritsa Ntchito Zamoyo: Onse formaldehyde ndi glutaraldehyde amapeza ntchito yayikulu m'munda wa zamankhwala.Amagwiritsidwa ntchito kwambiri pakukonza minofu ndikusunga mu histology ndi maphunziro a pathology.Minofu yophatikizika imasunga umphumphu wawo ndipo imatha kukonzedwanso pazolinga zosiyanasiyana zowunikira komanso kuzindikira.
Kulamulira kwa tizilombo toyambitsa matenda: Mankhwala onsewa ali ndi mphamvu zowononga tizilombo toyambitsa matenda, zomwe zimawapangitsa kukhala ofunika kwambiri popha tizilombo toyambitsa matenda ndi njira yotseketsa.Angathe kuletsa mabakiteriya, mavairasi, ndi bowa, kuchepetsa chiopsezo cha kuipitsidwa m'ma laboratories ndi zida zachipatala.
Ntchito Zamakampani: Onse formaldehyde ndiglutaraldehydeamagwiritsidwa ntchito m'mafakitale osiyanasiyana.Amagwiritsidwa ntchito popanga zomatira, zomatira, ma polima, komanso mafakitale a zikopa ndi nsalu.
Kusiyana:
Kapangidwe ka Chemical: Kusiyana kwakukulu pakati pa formaldehyde ndi glutaraldehyde kumakhala muzinthu zawo zama cell.Formaldehyde (CH2O) ndi aldehyde yosavuta kwambiri, yopangidwa ndi atomu imodzi ya kaboni, maatomu awiri a haidrojeni, ndi atomu imodzi ya okosijeni.Glutaraldehyde (C5H8O2), kumbali ina, ndi aliphatic aldehyde yovuta kwambiri, yomwe imakhala ndi maatomu asanu a carbon, maatomu asanu ndi atatu a haidrojeni, ndi maatomu awiri a okosijeni.
Reactivity: Glutaraldehyde nthawi zambiri imakhala yotakasuka kuposa formaldehyde chifukwa cha unyolo wake wautali wa kaboni.Kukhalapo kwa maatomu asanu a carbon mu glutaraldehyde kumapangitsa kuti pakhale mtunda wautali pakati pa magulu ogwira ntchito pa ma biomolecules, zomwe zimapangitsa kuti pakhale kuwoloka kofulumira komanso kothandiza kwambiri.
Kuchita Bwino Kwambiri: Chifukwa chakuchitanso bwino, glutaraldehyde nthawi zambiri imakhala yothandiza kwambiri pakuwoloka ma biomolecules akulu, monga mapuloteni ndi michere.Formaldehyde, ngakhale imatha kuphatikizika, imatha kutengera nthawi yochulukirapo kapena kupitilira apo kuti ikwaniritse zotsatira zofananira ndi mamolekyu akulu.
Poizoni: Glutaraldehyde imadziwika kuti ndi poizoni kuposa formaldehyde.Kuwonekera kwa nthawi yayitali kapena kofunika kwa glutaraldehyde kungayambitse khungu ndi kupuma, ndipo imatengedwa ngati sensitizer, kutanthauza kuti ikhoza kuyambitsa kusagwirizana ndi anthu ena.Mosiyana ndi zimenezi, formaldehyde ndi kansa yodziwika bwino ndipo imaika moyo pachiswe, makamaka ikakoka mpweya kapena kukhudza khungu.
Ntchito: Ngakhale mankhwala onsewa amagwiritsidwa ntchito pokonza minofu, nthawi zambiri amawakonda pazifukwa zosiyanasiyana.Formaldehyde imagwiritsidwa ntchito nthawi zonse popanga ma histological ndi kuumitsa mitembo, pomwe glutaraldehyde ndiyoyenera kusunga ma cell a cell ndi ma antigenic mu ma electron microscopy ndi maphunziro a immunohistochemical.
Kukhazikika: Formaldehyde imakhala yosasunthika ndipo imakonda kusanduka nthunzi mwachangu kuposa glutaraldehyde.Katunduyu amatha kukhudza kasamalidwe ndi kasungidwe kazinthu zolumikizirana.
Mwachidule, formaldehyde ndi glutaraldehyde amagawana mikhalidwe yofananira ngati ma crosslinking agents, koma amasiyana kwambiri ndi kapangidwe kake ka mankhwala, reactivity, kawopsedwe, ndi kugwiritsa ntchito kwawo.Kumvetsetsa koyenera kwa kusiyana kumeneku ndikofunikira pakusankha njira yoyenera yolumikizirana pazifukwa zinazake ndikuwonetsetsa kuti ikugwiritsidwa ntchito motetezeka komanso mogwira mtima muzochitika zosiyanasiyana zasayansi, zamankhwala, ndi mafakitale.
Nthawi yotumiza: Jul-28-2023