TriclosanNdi mankhwala opha tizilombo toyambitsa matenda osiyanasiyana omwe amagwiritsidwa ntchito ngati mankhwala opha tizilombo toyambitsa matenda, opha tizilombo toyambitsa matenda kapena osungira m'malo azachipatala, zinthu zosiyanasiyana zomwe anthu amagwiritsa ntchito kuphatikizapo zodzoladzola, zinthu zoyeretsera m'nyumba, zinthu zapulasitiki, zoseweretsa, utoto, ndi zina zotero. Amaphatikizidwanso pamwamba pa zipangizo zachipatala, zinthu zapulasitiki, nsalu, ziwiya zakukhitchini, ndi zina zotero, zomwe zimatha kutuluka pang'onopang'ono kwa nthawi yayitali akamazigwiritsa ntchito, kuti zigwire ntchito yake yowononga tizilombo toyambitsa matenda.
Kodi triclosan imagwiritsidwa ntchito bwanji mu zodzoladzola?
Triclosanidalembedwa mu 1986 mu European Community Cosmetics Directive kuti igwiritsidwe ntchito ngati chosungira mu zinthu zodzikongoletsera pamlingo wofika pa 0.3%. Kuwunika kwaposachedwa kwa zoopsa komwe kunachitika ndi EU Scientific Committee on Consumer Products kunatsimikiza kuti, ngakhale kuti kugwiritsidwa ntchito kwake pamlingo wopitilira 0.3% mu mankhwala otsukira mano, sopo wamanja, sopo wa thupi/ma gels osambira ndi ndodo za deodorant kumaonedwa kuti ndikotetezeka poganizira za poizoni muzinthu zosiyanasiyana, kuchuluka kwa kuwonetsa triclosan kuchokera kuzinthu zonse zodzikongoletsera sikotetezeka.
Kugwiritsa ntchito kwina kulikonse kwa triclosan mu ufa wa nkhope ndi zophimba mabala pamlingo uwu kunaonedwanso kuti ndikotetezeka, koma kugwiritsa ntchito triclosan muzinthu zina zosiya kusuta (monga mafuta odzola thupi) ndi mu zotsukira pakamwa sikunaonedwe kuti ndikotetezeka kwa ogula chifukwa cha kuchuluka kwa mpweya womwe umabwera chifukwa cha zinthu zopopera (monga ma deodorants) sikunayesedwe.
TriclosanPopeza si ya ionic, imatha kupangidwa m'ma dentifrices achikhalidwe. Komabe, siimalumikizana ndi malo opaka pakamwa kwa maola opitilira ochepa, motero siimapereka mphamvu yokhazikika yolimbana ndi ma plaque. Kuti muwonjezere kuyamwa ndi kusunga kwa triclosan ndi malo opaka pakamwa kuti muwongolere kuwongolera ma plaque ndi thanzi la genival, triclosan/polyvinylmethyl ether maleic acid copolymer ndi triclosan/zinc citrate ndi triclosan/calcium carbonate dentifrice zimagwiritsidwa ntchito.
Kodi triclosan imagwiritsidwa ntchito bwanji mu zipangizo zachipatala ndi zamankhwala?
Triclosanyagwiritsidwa ntchito bwino kuchipatala pochotsa tizilombo toyambitsa matenda monga Staphylococcus aureus (MRSA) yosagonjetsedwa ndi methicillin, makamaka ndi malangizo oti tigwiritse ntchito 2% ya triclosan bath. Triclosan imagwiritsidwa ntchito ngati scrubs pa opaleshoni, ndipo imagwiritsidwa ntchito kwambiri posamba m'manja komanso ngati kusamba thupi kuti tichotse MRSA kwa omwe ali ndi matendawa musanachite opaleshoni.
Triclosan imagwiritsidwa ntchito m'zida zingapo zachipatala, mwachitsanzo, ma stents a ureteral, ma sture opareshoni ndipo angaganizidwe kuti ateteze matenda a graft. Bojar ndi ena sanaone kusiyana pakati pa ma stures okhala ndi triclosan ndi ma sture okhazikika a multifilament, ngakhale kuti ntchito yawo inali yokhudza mabakiteriya asanu ndipo imangotengera kudziwa malo omwe akuletsa.
Mu ma stenti a mkodzo, triclosan yawonetsedwa kuti imaletsa kukula kwa mabakiteriya omwe amayambitsa matenda a uropathogens komanso kuchepetsa kuchuluka kwa matenda opatsirana m'mitsempha ya mkodzo, ndipo mwina, kutsekeka kwa catheter kwawonetsa zotsatira zogwirizana za triclosan ndi maantibayotiki oyenera pa mitundu isanu ndi iwiri ya matenda a uropathogen, ndipo amathandizira kugwiritsa ntchito stent ya triclosan-eluting ngati pakufunika kutero, pamodzi ndi mankhwala ochiritsira ochiritsira odwala ovuta.
Mu zina zomwe zachitika, kugwiritsa ntchito triclosan mu catheter ya Foley ya mkodzo kunanenedwa chifukwa triclosan inaletsa bwino kukula kwa Proteus mirabilis komanso kuletsa kwa catheter. Posachedwapa, Darouiche ndi anzake adawonetsa kuti ma catheter okhala ndi ma spectrum ambiri komanso okhazikika amalimbana ndi ma antibiotic a ma catheter okhala ndi triclosan ndi DispersinB, enzyme yotsutsana ndi biofilm yomwe imaletsa ndikufalitsa biofilms.
Kodi triclosan imagwiritsidwa ntchito bwanji mu zinthu zina zogwiritsidwa ntchito ndi anthu?
Mphamvu ya triclosan yolimbana ndi mavairasi ambiri yapangitsa kuti iphatikizidwe mu mitundu yosiyanasiyana ya mankhwala omwe amagwiritsidwa ntchito kunyumba monga sopo wamadzimadzi, sopo wothira madzi, matabwa odulira, zoseweretsa za ana, makapeti ndi ziwiya zosungiramo chakudya. Mndandanda wazinthu zomwe ogula amagwiritsa ntchito zomwe zili ndi triclosan waperekedwa ndi US Environmental Protection Agency (EPA) ndi mabungwe omwe siaboma aku US "Environmental Working Group" ndi "Beyond Pesticides".
Zinthu zambiri zogulira zovala zimachiritsidwa ndi mankhwala ophera tizilombo toyambitsa matenda. Triclosan ndi imodzi mwa zinthu zomalizitsa kupanga nsalu zotere. Nsalu zomwe zimamalizidwa ndi triclosan zimachiritsidwa ndi zinthu zolumikizirana kuti zikhale ndi mphamvu zolimba zotsutsana ndi mabakiteriya. Kutengera ndi zomwe zilipo, zinthu 17 zochokera kumsika wogulitsa ku Denmark zidasanthulidwa kuti zione kuchuluka kwa mankhwala ena oletsa mabakiteriya: triclosan, dichlorophen, Kathon 893, hexachlorophen, triclocarban ndi Kathon CG. Zinthu zisanu mwa zinthuzi zidapezeka kuti zili ndi 0.0007% - 0.0195% triclosan.
Aiello ndi anzake mu kafukufuku woyamba wofufuza ubwino wa sopo wokhala ndi triclosan, adafufuza maphunziro 27 omwe adasindikizidwa pakati pa 1980 ndi 2006. Chimodzi mwa zomwe zapezeka ndichakuti sopo wokhala ndi triclosan yochepera 1% sanawonetse phindu lililonse kuchokera ku sopo yopanda maantibayotiki. Kafukufuku yemwe adagwiritsa ntchito sopo wokhala ndi > 1% triclosan adawonetsa kuchepa kwakukulu kwa mabakiteriya omwe alipo, nthawi zambiri akagwiritsidwa ntchito kangapo.
Kusagwirizana pakati pa kugwiritsa ntchito sopo wokhala ndi triclosan ndi kuchepa kwa matenda opatsirana kunali kovuta kudziwa popanda kuzindikira zinthu zomwe zimayambitsa zizindikiro za matendawa. Kafukufuku waposachedwapa wa ku America wasonyeza kuti kusamba m'manja ndi sopo wopha tizilombo toyambitsa matenda wokhala ndi triclosan (0.46%) kumachepetsa kuchuluka kwa mabakiteriya ndi kusamutsa mabakiteriya m'manja, poyerekeza ndi kusamba m'manja ndi sopo wopanda mankhwala opha tizilombo toyambitsa matenda.
Zogulitsa za Masika
Timapanga zinthu zosiyanasiyana zomwe zingagwiritsidwe ntchito mu makampani osamalira thupi ndi zokongoletsa, monga chisamaliro cha khungu, chisamaliro cha tsitsi, chisamaliro cha pakamwa, zodzoladzola, kuyeretsa m'nyumba, chisamaliro cha sopo ndi zovala, kuyeretsa kuchipatala ndi m'mabungwe aboma. Lumikizanani nafe tsopano ngati mukufuna mnzanu wodalirika wabizinesi.
Nthawi yotumizira: Juni-10-2021