Chilichonse Chimene Muyenera Kudziwa Zokhudza Glutaraldehyde

Glutaraldehyde 25%ali ndi zolimbikitsa ndi kuchiritsa zotsatira pa khungu la munthu ndi mucous zimagwira ntchito zosiyanasiyana ndipo angayambitse ziwengo, choncho sayenera kugwiritsidwa ntchito pophera tizilombo mu mpweya ndi chakudya ziwiya.Kuphatikiza apo, glutaraldehyde sayenera kugwiritsidwa ntchito popha tizilombo toyambitsa matenda komanso kutsekereza zida zachipatala za tubular, singano za jakisoni, ma suture opangira opaleshoni ndi ulusi wa thonje.

Glutaraldehyde imagwiritsidwa ntchito kwambiri ngati mankhwala ophera tizilombo m'makampani azachipatala ndipo ogwiritsa ntchito amatha kukhala ndi mafunso okhudzana ndiukadaulo, kotero Springchem pano imapereka mfundo zazikulu za glutaraldehyde kuti mufotokozere.

Akuchuluka kwa glutaraldehyde

Glutaraldehyde imagwiritsidwa ntchito ngati sterilant yozizira kupha zida zomwe sizimva kutentha, monga endoscopes ndi zida za dialysis.Amagwiritsidwa ntchito ngati mankhwala opha majeremusi apamwamba pazida zopangira maopaleshoni zomwe sizingatenthedwe kutentha.

Glutaraldehyde imagwiritsidwa ntchito pazinthu zingapo m'zipatala:

● Chothandizira minyewa m'ma laboratories

● Mankhwala ophera tizilombo komanso ophera tizilombo toyambitsa matenda pamalo ndi zipangizo

● Makina owumitsa mtima omwe amagwiritsidwa ntchito popanga ma X-ray

● Pokonzekera kumezanitsa

Kutha ntchitotsiku la glutaraldehyde ndi momwe mungadziwire nthawi yake

Pa kutentha kwa firiji komanso pansi pa chikhalidwe chokhala kutali ndi kuwala ndi kusungidwa kosindikizidwa, tsiku lotha ntchito ya glutaraldehyde sayenera kupitirira zaka 2, ndipo chogwiritsira ntchito cha glutaraldehyde chiyenera kukhala osachepera 2.0% mkati mwa tsiku lotha ntchito.

Kutentha kwapakati, mutatha kuwonjezera dzimbiri inhibitor ndi pH adjuster, glutaraldehyde imagwiritsidwa ntchito pa chipangizo chachipatala chomiza disinfection kapena chotseketsa, ndipo chingagwiritsidwe ntchito kwa masiku 14 opitirira.Zomwe zili mu glutaraldehyde ziyenera kukhala zosachepera 1.8% pakagwiritsidwe ntchito.

Kumizadmatendanjirandi glutaraldehyde

Zilowerereni zida zotsukidwazo mu 2.0% ~ 2.5% glutaraldehyde disinfection solution kuti muzizimitse kwathunthu, kenaka phimbani chidebe chophera tizilombo pa kutentha kwa firiji kwa mphindi 60, ndikutsuka ndi madzi osabala musanagwiritse ntchito.

Zida zotsukidwa ndi zouma zowunikira komanso zochizira, zida ndi zida zimayikidwa mu 2% ya alkaline glutaraldehyde solution yomizidwa kwathunthu, ndipo thovu lamlengalenga lomwe lili pamwamba pa zida liyenera kuchotsedwa ndi chidebe chophimbidwa ndi kutentha kwa 20 ~ 25 ℃.Disinfection imagwira ntchito mpaka nthawi yodziwika ya malangizo azinthu.

Zofunikira pakuphetsa ma endoscopes ndi glutaraldehyde

1. High mlingo disinfection ndi yotseketsa magawo

● Kukhazikika: ≥2% (zamchere)

● Nthawi: bronchoscopy disinfection kumizidwa nthawi ≥ 20min;ena endoscopes disinfection ≥ 10min;Kumiza kwa endoscopic kwa odwala omwe ali ndi chifuwa chachikulu cha mycobacterium, mycobacteria ndi matenda ena apadera ≥ 45min;kutsekereza ≥ 10h

2. Gwiritsani ntchito njira

● Makina oyeretsera ma endoscope ndi kupha tizilombo toyambitsa matenda

● Kugwira ntchito pamanja: mankhwala ophera tizilombo ayenera kudzazidwa ndi chitoliro chilichonse ndikuviika kuti tizilombo toyambitsa matenda

3. Njira zodzitetezera

Glutaraldehyde 25%ndi allergenic ndipo amakwiyitsa khungu, maso ndi mpweya, ndipo angayambitse dermatitis, conjunctivitis, kutupa kwa m'mphuno ndi mphumu yapantchito, choncho iyenera kugwiritsidwa ntchito poyeretsa endoscope ndi makina ophera tizilombo.

Kusamala ndi glutaraldehyde

Glutaraldehyde imakwiyitsa khungu ndi mucous nembanemba komanso poizoni kwa anthu, ndipo njira ya glutaraldehyde imatha kuwononga kwambiri maso.Choncho, ziyenera kukonzedwa ndikugwiritsidwa ntchito pamalo abwino mpweya wabwino, chitetezo chaumwini chiyenera kukonzekera bwino, monga kuvala masks otetezera, magolovesi otetezera ndi magalasi otetezera.Ngati mwakumana naye mosadziwa, ayenera kuthiriridwa nthawi yomweyo ndi madzi mosalekeza, ndipo ngati maso avulala, angafunikire chithandizo chamankhwala msanga.

Ayenera kugwiritsidwa ntchito pamalo olowera mpweya wabwino, ndipo ngati kuli kofunikira, malowo azikhala ndi zida zotulutsa mpweya.Ngati kuchuluka kwa glutaraldehyde mumlengalenga pamalo ogwiritsidwa ntchito ndikokwera kwambiri, tikulimbikitsidwa kuti mukhale ndi zida zopumira zokha (chigoba choteteza kupanikizika).Zotengera zomwe zimagwiritsidwa ntchito pouzira zimayenera kukhala zoyera, zophimbidwa komanso zopha tizilombo tisanagwiritse ntchito.

Kuwunika pafupipafupi ndende ya glutaraldehyde

Kuchuluka kwa glutaraldehyde kumatha kuyang'aniridwa ndi mizere yoyesera mankhwala.

Mukamagwiritsa ntchito mosalekeza, kuyang'anira tsiku ndi tsiku kuyenera kulimbikitsidwa kuti mumvetsetse kusintha kwake, ndipo sayenera kugwiritsidwa ntchito pokhapokha ndende yake ikapezeka pansi pamlingo wofunikira.

Ziyenera kutsimikiziridwa kuti kuchuluka kwa glutaraldehyde komwe kumagwiritsidwa ntchito kumakwaniritsa zofunikira za buku lazogulitsa.

Ayeneraglutaraldehyde iyenera kuyatsidwa musanagwiritse ntchito?

Madzi amadzimadzi a glutaraldehyde ndi acidic ndipo nthawi zambiri sangaphe timbewu tating'ono tambiri timene timatulutsa acidic.Ndi pamene yankho "lidatsegulidwa" ndi alkalinity ku pH mtengo wa 7.5-8.5 kuti ikhoza kupha spores.Akatsegulidwa, mayankhowa amakhala ndi alumali moyo wamasiku osachepera 14.Pamilingo ya pH ya alkaline, mamolekyu a glutaraldehyde amayamba kupanga polymerize.Kuphatikizika kwa glutaraldehyde kumapangitsa kutsekedwa kwa gulu la aldehyde la molekyulu yake ya glutaraldehyde yomwe imayambitsa kupha spores, motero mphamvu ya bakiteriya imachepa.

Zomwe zimakhudza kutsekeka kwa glutaraldehyde

1. Nthawi yokhazikika komanso yochitapo kanthu

Mphamvu ya bactericidal idzakulitsidwa ndikuwonjezeka kwa ndende komanso kukulitsa nthawi yochitapo kanthu.Komabe, yankho la glutaraldehyde lomwe lili ndi gawo lalikulu la zosakwana 2% silingakwaniritse zotsatira zodalirika za bactericidal pa spores za bakiteriya, ziribe kanthu momwe mungakulitsire nthawi ya bactericidal.Chifukwa chake, ndikofunikira kugwiritsa ntchito njira ya glutaraldehyde yokhala ndi gawo lalikulu kuposa 2% kupha tizilombo ta bakiteriya.

2. Kuthetsa acidity ndi alkalinity

Mphamvu ya bactericidal ya asidi glutaraldehyde ndiyotsika kwambiri kuposa ya alkaline glutaraldehyde, koma kusiyanako kudzachepa pang'onopang'ono ndi kutentha kwakukulu.Pazigawo za pH 4.0-9.0, mphamvu ya bakiteriya imawonjezeka ndikuwonjezeka pH;mphamvu ya bactericidal kwambiri imawonedwa pa pH 7.5-8.5;pa pH> 9, glutaraldehyde imasungunuka mwachangu ndipo mphamvu ya bactericidal imatayika mwachangu.

3. Kutentha

Imakhalanso ndi bactericidal zotsatira pa kutentha kochepa.Mphamvu ya bactericidal ya glutaraldehyde imawonjezeka ndi kutentha, ndipo kutentha kwake (Q10) ndi 1.5 mpaka 4.0 pa 20-60 ℃.

4. organic kanthu

Organic kanthu imapangitsa bactericidal mphamvu kukhala yofooka, koma zotsatira za organic kanthu pa bactericidal zotsatira za glutaraldehyde ndi zazing'ono kuposa mankhwala ena opha tizilombo.20% seramu ya ng'ombe ndi 1% yamagazi athunthu alibe mphamvu pa 2% glutaraldehyde.

5. Synergistic zotsatira za nonionic surfactants ndi zina physicochemical zinthu

Polyoxyethylene fatty alcohol ether ndi nonionic surfactant, ndipo kukhazikika ndi bactericidal zotsatira zimakhala bwino kwambiri powonjezera 0,25% polyoxyethylene fatty alcohol ether ku glutaraldehyde solution yopangidwa ndi asidi-base glutaraldehyde yowonjezera.Ultrasound, kuwala kwakutali kwa infrared ndi glutaraldehyde zimakhala ndi synergistic sterilization effect.

Springchem, wopanga ma glutaraldehyde 10 apamwamba kwambiri ku China, amapereka glutaraldehyde 25% ndi 50% pamafakitale, labotale, zaulimi, zachipatala, ndi zina zapakhomo, makamaka popha tizilombo toyambitsa matenda ndikuchotsa malo ndi zida.Kuti mudziwe zambiri, ingolumikizanani nafe.