Climbazolendi Piroctone Olamine onse ndi zosakaniza zomwe zimagwiritsidwa ntchito popanga shampu polimbana ndi dandruff.Ngakhale kuti amagawana zinthu zofanana za antifungal ndipo amayang'ana zomwe zimayambitsa dandruff (bowa la Malassezia), pali kusiyana pakati pa mankhwala awiriwa.
Kusiyanitsa kumodzi kwakukulu kwagona pamachitidwe awo.Climbazoleimagwira ntchito poletsa biosynthesis ya ergosterol, chigawo chachikulu cha nembanemba yama cell a mafangasi.Mwa kusokoneza nembanemba ya selo, climbazole imapha bwino bowa ndikuchepetsa dandruff.Kumbali ina, Piroctone Olamine imagwira ntchito posokoneza kupanga mphamvu mkati mwa maselo a fungal, zomwe zimapangitsa kuti awonongeke.Zimasokoneza ntchito ya mitochondrial ya bowa, kusokoneza mphamvu yake yopanga mphamvu ndikukhala ndi moyo.Kusiyanasiyana kwa machitidwewa kumasonyeza kuti akhoza kukhala ndi mphamvu zosiyana siyana motsutsana ndi mitundu yosiyanasiyana ya Malassezia.
Kusiyanitsa kwina kodziwika ndi kusungunuka kwawo.Climbazole imasungunuka kwambiri m'mafuta kuposa madzi, zomwe zimapangitsa kuti zikhale zoyenera kupanga shampu yopangidwa ndi mafuta kapena emulsion.Komano, piroctone Olamine imasungunuka kwambiri m'madzi, zomwe zimapangitsa kuti zikhale zosavuta kuziyika mu shampoos zamadzi.Kusankha pakati pa climbazole ndi Piroctone Olamine kungadalire kapangidwe kake ndi zomwe wopanga angakonde.
Pankhani ya chitetezo, onse a climbazole ndi Piroctone Olamine ali ndi mbiri yabwino yokhala ndi zotsatira zochepa.Amaonedwa kuti ndi otetezeka kuti agwiritsidwe ntchito pamutu, ngakhale kukhudzidwa kwapayekha kapena ziwengo zitha kuchitika.Nthawi zonse tikulimbikitsidwa kutsatira malangizowo ndikuwonana ndi akatswiri azachipatala ngati mukukumana ndi zovuta zilizonse.
Ma shampoos nthawi zambiri amaphatikizanaclimbazolekapena Piroctone Olamine yokhala ndi zinthu zina zomwe zimagwira ntchito kuti zithandizire kulimbana ndi dandruff.Mwachitsanzo, amatha kuphatikizidwa ndi zinc pyrithione, selenium sulfide, kapena salicylic acid kuti apereke njira yokwanira yothanirana ndi dandruff.
Mwachidule, pamene onse a climbazole ndi Piroctone Olamine ali othandiza antifungal agents omwe amagwiritsidwa ntchito popanga shampu, amasiyana m'machitidwe awo komanso kusungunuka kwawo.Kusankha pakati pa ziwirizi kungadalire zokonda za kapangidwe kake komanso mawonekedwe ofunikira a shampoo.
Nthawi yotumiza: Jun-13-2023